Good Sleep. Great Tomorrow.

Welcome to the

Sleep Medicine Institute of Texas

FDA News :AIO Breathe® is FDA-cleared for adults (18+) as of 02/23/2024 - now joined by the newly FDA-cleared pediatric AIO Breathe® (ages 6-17) on 11/06/2025.
World’s first pediatric AIO Breathe® dispensed at Sleep Medicine Institute of Texas on 02/02/2026.


National Recognition & Peer-Reviewed Support

AIO Breathe® has been presented at national sleep medicine conferences and is supported by multiple peer-reviewed publications.

AMERICA250 4TH OF JULY SALE

10% DISCOUNT on all products.
25% DISCOUNT for Veterans, Active Military, Teachers, and First Responders on AIO Breathe® devices for Sleep Apnea (OSA).
FOR A LIMITED TIME ONLY!!!


AIO Breathe® for Sleep Apnea

AIO Breathe® for adults is $2,695.
Pediatric AIO Breathe® is available through our Unlimited Devices Subscription Program.
Call 903-787-7533 to learn how to get yours.


SLEEP STUDIES (IN-CENTER & HOME)

We offer the fastest, most comprehensive sleep testing program in Texas - for both adults and children.

In-Center Sleep Studies

Adult in-center sleep study: $899
Pediatric in-center sleep study: $1,699
Performed in our state-of-the-art sleep rooms with full medical monitoring.

Home Sleep Study Program

Disposable Home Sleep Study - $295
Single-use, medical-grade test. No returns. No wires.
Ideal for fast, simple, one-night testing.

World’s Smallest Home Sleep Study - $265
A fingertip-only device - the smallest home sleep study in the world.
Perfect for children, athletes, and anyone who wants zero wires and maximum comfort.

Fast-Track Access

Sleep studies completed by the next day - compared to the national average of 6-9 months.
Our Fast-Track system eliminates long waitlists and gets patients diagnosed and treated immediately.


WEIGHT LOSS, METABOLIC HEALTH & BROSAR PROGRAMS

Physician-designed programs for adults, children, and athletes.

BROSAR-8

An 8-step system for body recomposition and OSA reduction, integrating nutrition, hydration, exercise, sleep optimization, metabolic tracking, airway biomechanics, behavioral coaching, and recovery science.

BROSAR-9

A 9-module program for youth athletes, adult athletes, and high-performance professionals.
Includes airway optimization, VO2 max enhancement, metabolic conditioning, recovery science, and AIOMEGA performance tracking.

AIOMEGA App Integration

Tracks weight, HRV, exercise, metabolic targets, sleep, and AIO Breathe® progress.


GLP-1 WEIGHT LOSS PROGRAM

Our physician-supervised GLP-1 program provides safe, structured metabolic weight loss using modern incretin-based therapies.

Program includes medical evaluation, GLP-1 therapy (semaglutide/tirzepatide class), nutrition and hydration protocols, sleep optimization, weekly progress tracking, and AIOMEGA App integration for weight, HRV, and metabolic metrics.

GLP-1 therapy supports appetite control, satiety, metabolic improvement, and OSA reduction when combined with airway therapy.

Fully integrated with BROSAR-8 and BROSAR-9 for enhanced fat loss, metabolic control, athletic performance, and recovery.


INNOVATION & TECHNOLOGY LEADERSHIP

Innovation at Sleep Medicine Institute of Texas is led by Dr. Raghavendra Ghuge - physician-inventor of multiple FDA-cleared airway technologies spanning airway biomechanics, robotics, cardiology, and AI-guided device design.


AIO BREATHE® - FDA-CLEARED AIRWAY TECHNOLOGY

Adults FDA-cleared: 02/23/2024
Pediatrics FDA-cleared: 11/06/2025
First pediatric AIO Breathe® dispensed: 02/02/2026

Patented Connected Arc-of-Motion and REVIVE On-Demand Airflow increase airway size without forcing the jaw forward.


DR. GHUGE - U.S. PATENTS (UPDATED & COMPLETE)

Granted Patents

US 12,029,679 - Advanced airway device architecture
US 11,819,449 - Airflow optimization system
US 11,806,273 - Mandibular-lingual repositioning mechanisms
US 11,666,477 - Oral appliance robotics
US 11,666,478 - Dynamic robotic airway management
US 11,484,434 - Multi-vector airway enlargement
US 11,484,435 - Airway stabilization technology
US 12,318,325 - Integrated airway device systems
US 12,376,987 - Automated airway repositioning robotics
US 12,478,500 - Mandibular repositioning robotics
US 12,485,036 - Adaptive oral appliance robotics
US 12,589,180 - Multi-camera intraoral imaging system

US 12,636,127-B2 - Craniofacial Growth, Palatal Expansion & Bone Remodeling System
Polymeric nanocomposite growth-modulation system enabling controlled expansion of the palate, maxilla, and mandible, supporting airway development and craniofacial remodeling.

US (Rapid Fracture Healing & Bone Growth Acceleration)
Nanocomposite polymeric splints delivering mechanotransductive micro-strain to accelerate fracture healing, callus formation, and directional bone regeneration.

Pending Applications

US 2025/0339307 - Oral appliance robotics
US 2025/0288454 - Airway optimization
US 2025/0090367 - Mandibular-lingual repositioning
US 2024/0342001 - Airway device sensors
NP-A - Device & Kit
NP-B - Method & Treatment
NP-C - System, Sensors & Robotics

New PCT Filing

PCT/US26/31913 - AI-Guided Construction of Mandibular Advancement Device Architecture and Methods Relating Thereto
AI-driven generation of device geometry, predictive airway modeling, and algorithmic optimization.


ADDITIONAL EXPERTISE

CPAP/BIPAP Expertise

Over two decades of PAP therapy experience.
State-of-the-art sleep rooms for mask fittings and PAP trials.

Clinical Discoveries

BIPAP reduces blood pressure more effectively than CPAP.
BIPAP can reverse pulmonary artery hypertension.
BIPAP + Mandibular Devices can reduce water retention by up to 21 lbs.

AIO Breathe® for CPAP-Intolerant Patients

Custom-built oral appliance for adults and children.
Call 903-787-7533 to see if AIO Breathe® is right for you.

Complete Sleep Care Under One Roof

Consultation → Testing → CPAP/BIPAP → AIO Breathe® → Supplies → Follow-up

THEPAPSTORE.com

Global digital platform for sleep tests, PAP devices, masks, supplies, and AIO Breathe®.

Fast Access to Care

New-patient coordinator contacts you within 1-2 days.
Telemedicine available.

We Welcome All Patients

Even if you tested elsewhere or get supplies elsewhere - we are here to help you achieve Good Sleep for a Great Tomorrow.

Sleep Tyler

Sleep Clinic

The Clinic at Sleep Medicine Institute of Texas offers detailed hands on physical exams and comprehensive consultative services by a board certified and fellow-ship trained sleep physician with over 25 years of experience successfully treating sleep disorders in adults, teenagers and children of all ages.

We offer all medical treatment options for sleep apnea in adults and children including PAP therapy, a new and innovative oral appliance AIO BREATHE with patented designs by our very own Physician Dr. Ghuge, medications  and recommend surgical options when indicated. We have emphasis on detection and diagnosis of cardiovascular, neurological and other medical conditions linked to Sleep Disorders.

Dr. Ghuge designed, patented and built the AIOMEGA APP geared towards integration of holistics, natural weight loss programs, healthy hydration and customized fitness programs. AIOMEGA APP has friendly and easy to use widgets that are powered by complex AI driven algorithms from Dr. Ghuge's patented inventions. It is freely available in the Apple AppStore and on Google Play Store. AIOMEGA App is a great tool for those with metabolic syndrome or people who struggle with ups and downs in weight or resistant weight loss and even those who seek weight gain and growth in strength and speed or endurance. It is a Unique method to align high end technology with ease-of-use and compliments CPAP/BIPAP therapy and AIO BREATHE therapy with weight loss and hydration. We use trackable graphs and adjustable individually customized planning that is at the heart of AIOMEGA APP to help evaluate cardiovascular, sleep, metabolic and other conditions while offering clear direction to weight loss programs and healthy heart plans.

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Sleep Laboratory

The Sleep Lab at Sleep Medicine Institute of Texas provides world class quality and comfort using the leading brand of sleep technology. Having the Sleep Lab at the same location as the Sleep Clinic builds trust and confidence while making it convenient and comfortable to spend the night.

The technology of recording blood pressure with every heart beat is unique to Sleep Medicine Institute in North East Texas. We are the only Sleep Lab that offers this technology and generate data that help us diagnose Sleep Induced Hypertension. This condition can cause strokes or heart attacks in people who may have normal blood pressure during wake hours. We were the first to prove BIPAP therapy could cure Sleep Induced hypertension and we were the first to  prove that pulmonary hypertension associated with Obstructive Sleep Apnea can be cured with BIPAP therapy.

Our highly qualified sleep technologists will make your stay very comfortable. The environment at The Sleep Lab will be quiet and peaceful and the technologist provides compassionate care to put your mind to rest.

At-home sleep studies are also performed by The Sleep Lab at Sleep Medicine Institute of Texas. 

The Institute works with your insurance company to get preauthorizations or approvals on your behalf. We have the quickest turn-around time for performing sleep studies, whether they are in The Sleep Lab or at-home.

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AIO BREATHE Oral Appliance for Sleep Apnea and Snoring


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Why AAVOAT and AIO BREATHE® Should Be Your First Choice in Oral Appliance Therapy

AIO BREATHE®: A New Standard for Airway-Focused Oral Appliance Therapy


AAVOAT with AIO BREATHE® offers a modern, airway-first approach to oral appliance therapy for obstructive sleep apnea (OSA) and snoring. Designed around the natural movement of the jaw, AIO BREATHE® helps support airway opening during sleep while remaining small, lightweight, quiet, non-surgical, and travel-friendly.

For adults with snoring and mild to moderate OSA, AIO BREATHE® provides an FDA-cleared treatment option that may be especially helpful for patients who prefer an alternative to CPAP/BIPAP or have difficulty tolerating PAP therapy.

  • Custom oral appliance therapy guided by sleep medicine and dental expertise
    • Designed to support airway opening in both open-mouth and closed-mouth positions
      • Comfortable, compact, quiet, non-invasive, and easy to travel with
        • May improve treatment acceptance for patients who struggle with PAP therapy
          • Supports an airway-first mindset for both adult and pediatric sleep-disordered breathing care

Severe OSA consideration: CPAP/BIPAP remains the usual first-line therapy for severe OSA. However, in carefully selected adults where PAP therapy, other treatments, or surgery have failed, are not tolerated, are declined, or are not viable, oral appliance therapy may be considered as part of a physician-directed, dentist-managed treatment plan with objective follow-up sleep testing.

For children and adolescents, sleep-disordered breathing requires early screening, medical referral when appropriate, and coordinated care tailored to growth, development, airway anatomy, and clinical needs.

Take the next step: If snoring, fatigue, poor sleep, or CPAP intolerance is affecting your health or your child’s well-being, ask about an airway-focused evaluation and whether AAVOAT with AIO BREATHE® may be appropriate.

Clinical note: Treatment decisions should be made by qualified medical and dental professionals. AIO BREATHE® adult use is for snoring and mild to moderate OSA; severe OSA and pediatric cases require appropriate medical oversight, documentation, and follow-up.


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Durable Medical Equipment

The DME at Sleep Medicine Institute provides every popular brand of CPAP/BIPAP/APAP machines and all varieties of masks and supplies. Its convenient location at the Sleep Medicine Institute of Texas makes it easy to get your supplies and doctor visits at the same place.

We regularly ship supplies to all our customers all over the US and overseas to 5 continents. We provide 25 years of Physician/Staff expertise to patients who want to be set up on new CPAP/BIPAP therapy.

Our convenient comfortable sleep rooms are available to our patients for fitting and trial sessions.

The sleep physician is right here to help determine the right mask and the right pressure for the CPAP or BIPAP machine and you can get supplies for your machine and mask.

The DME works with your insurance company to get preauthorizations or approvals on your behalf so you can get your supplies regularly.

For those that prefer full control over their sleep equpment, supplies, sleep clinic care or sleep studies, ThePapStore: CPAP Masks Sleep Well Home Sleep Test Health Fitness is first unique digital platform to provide all of these in one marketplace for seamless end-to-end patient controlled management of sleep disorders. We would be happy to answer any questions about how to access our platform.

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Sleep Disorders Impact all areas of Health

Sleep disorders may reduce quality of life. OSA may cause or exacerbate heart disease such as coronary artery disease and atrial fibrillation. OSA may increase or cause neuro-degenerative conditions such as Dementia or Parkinson's Disease. Untreated OSA may cause or increase depression, ADD/ADHD, chronic headaches, weight gain, diabetes and many more medical conditions.

At Sleep Medicine Institute we take pride in a holistic approach to health. We believe integrating health with fitness, nutrition and sleep, hydration and metabolism, tracking of health metircs and sharing them with physicians who share the same values and ideals as their patients is super critical to successful maintenance of health and wellbeing. We believe this approach will save lives and reduce the cost and complications in health care.

Our physician, Dr. Ghuge, is the founder of AIOMEGA LLC, a biotechnology company. AIOMEGA supports all health and fitness organizations to fulfill their goals to make and keep Americans Healthy. With this goal in mind AIOMEGA LLC launched its first integrative health and fitness App, AIOMEGA. This is the first of its kind to connect physicians with patients and fitness coaches with athletes to create meaningful solutions for both groups customers. We believe, Physicians can now support their patient's dreams to create and maintain better health.

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Integrated approach to treatment of Sleep Disorders

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The road to better sleep starts with a thorough evaluation of your symptoms and clinical examination to understand underlying conditions that are associated with development of a sleep disorder. We harness an integrated approach and build a holistic plan while designing therapeutics for sleep disorders. These include patient inputs and preferences and sound scientific principles. 

Diagnostics include testing required for nay organ system that may play a role in the development of sleep disorders or might be adversly affected by the presence of a sleep disorder. We routinely screen for cardiovascular conditions like pulmonary artery hypertension and thickening of heart muscle because these may be associated with the presence of a sleep disorder. Variety of sleep tests and cardio-pulmonary, hormone or neurological tests my also be appropriately performed. 

    • Initial Evaluation by a Sleep Physician including history taking and physical examinations.
    • Appropriate Testing for Sleep Disorders
    • Cardiovascular tests like Echocardiography.
    • Pulmonary testing
    • Testing for acid reflux
    • Testing for hormonal imbalances
    • Dental evaluation
    • Effective Treatment Strategies for Restful Sleep
    • Discussion and planning with each patient is customized to the care of the patient
    • Patient inputs and feedback are carefully incorporated in management of treatment plan.
    • Patient preferences are included in decision making.
    • Follow-up Care is regularly performed 
    • Remote monitoring of therapy 
    • Use of AIOMEGA APP
    • Holistic integrative approach to management of the patient as a whole.
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Newsroom

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FDA clears AIOMEGA’s AIO Breathe, for treatment of Obstructive Sleep Apnea.

February 23, 2024, Tyler, Texas, USA.

AIOMEGA, a Texas biomedical company, announced that AIO BREATHE, their medical device that treats Obstructive Sleep Apnea, has been cleared by the Food and Drug Administration.

AIO BREATHE is a “new mandibular repositioning device” designed by Tyler, Texas based Board Certified Sleep Physician Dr. Raghavendra V. Ghuge, MD, MBA, DABSM, FAASM. Ghuge is the founder and CEO of AIOMEGA.

“I designed AIO BREATHE, supported by multiple patents, to overcome several shortcomings of conventional oral appliances used for treatment of OSA”, said Dr. Ghuge

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AIO Breathe Summary

AIO Breathe acts by increasing the patient’s airway during sleep, improving ability to exchange air, thereby reducing the tendency to snore and alleviating signs of obstructive sleep apnea.

AIO Breathe features right and left protrusive flanges that engage with corresponding right and left vertical flanges. This engagement repositions the jaw to reflect the dentist’s prescribed anterior mandibular advancement and is maintained while mouth is open or closed.

Additionally, mandibular plateaus guide the mandible downward, thus opening the anterior airway. The plateaus and flanges allow vertical opening of the jaw and work together to maintain advancement in open and closed mouth positions.

Indications for Use

AIO Breathe is intended to reduce or alleviate snoring and mild to moderate Obstructive Sleep Apnea (OSA) while sleeping in adults.

General Information

The unique features of this Mandibular Repositioning Device along with light weight and small formfactor provides an attractive option for those who seek treatment of OSA.

OSA, a chronic medical sleep disorder affecting about 30% of the world’s population, is associated with lifelong oxygen deprivation and snoring during sleep. This may result in many cardiovascular and neurological complications such as Hypertension, Atrial Fibrillation, stroke, congestive heart failure and metabolic complications such as obesity and Diabetes. The conventional treatment of OSA is a CPAP device although a significant number of patients refuse or fail such therapy, and many are reluctant to seek help on account of hearing negative reports about CPAP. AIOMEGA’s AIO Breathe could provide a comfortable, convenient method of treatment to people around the world.

For the Public: Phone (903) 787-7533 or go to www.sleeptyler.com to use our contact us form. They can also email us at info@aiomd.com. 

Sleep Medicine Institute of Texas, PA

www.aiomd.com; www.thepapstore.com; www.sleeptyler.com

Ph: (903) 787-7533                     Fax: (903) 787-8825                  email: info@aiomd.com

Schedule an Appointment Today

There are over 80 sleep disorders. Recent studies show that over 80 million people in the U.S. suffer from a chronic sleep disorder, and almost 50% of Americans will have a sleep disorder at some point in their lifetime. To find out if you might be suffering from a sleep disorder, schedule an appointment today.

(903) 787-7533


American Academy of Sleep Medicine
The Sleep Medicine Institute of Texas
is an American Academy of Sleep Medicine Accredited Sleep Disorders Center